The Data Science Platform facilitates the development, management, analysis, and linkage of clinical, administrative, genomic and other data resources for patient-oriented research. The Platform works closely with the Manitoba Centre for Health Policy (MCHP), Regional Health Authorities, Manitoba Health, Seniors and Active Living, Public Health Agency of Canada, Canada Institute for Health Information, other provincial/ territorial SPOR SUPPORT Units, and other stakeholders.
Scientists lead and participate in a variety of projects to improve patient outcomes. Methodological innovations have focused on:
- Modelling of genomics and microbiome data
- Database quality assessment
- Population health surveillance methods
- Disease risk prediction models
- Measuring and modeling latent variables, such as health-related quality of life
Our team offers a range of short courses, workshops, and seminars including:
- Biostatistics group consulting sessions
- Workshops on advanced statistical methods, such as propensity score models and missing data models
- Resident training sessions on introductory biostatistics
- Bioinformatics workshops
- Introductory and intermediate clinical data management workshops
- Internships for undergraduate and graduate students
UPCOMING TRAINING & EVENTS
Click here for current training opportunities at CHI.
The Biostatistics Group serves as a resource of statistical expertise for researchers and students across the University of Manitoba, as well as at other universities. Expertise is provided in design, measurement, and analysis of health and health-related data.
The Biostatistics Group operates on a cost recovery model, however, there are accommodations for students and faculty members who do not have funds to support their research.
Examples of academic collaborations include:
• Consults on research design, data collection, data analysis, and results interpretation.
• Develops and adapts new research methods for research projects.
• Participates in grant planning, and proposal development.
• Provides advice on statistical computing for a variety of software, including SAS, SPSS, R and M-plus.
• Sample size and power calculations.
Support for New Clinician Scientists
The Biostatistics Group offers multiple training opportunities for the next generation of clinician scientists. The Royal College of Physicians and Surgeons has added a new scholarly competency to their training standards for resident and fellows (CanMEDS 2015), which will oblige trainees to formally study research methods and conduct a scholarly or research project during their training. To support resident and fellow research, the Biostatistics Group offers the following complementary programs and services:
- Open House sessions, where residents and fellows can meet one or more biostatistical consultants to discuss their study design and analysis questions. These sessions are co-sponsored by the College of Medicine’s Office of Postgraduate Medical Education (PGME). Registration is required, but there are no costs to participate. Please contact the PGME office for more information (email@example.com).
- A series of 3 academic half day workshops on statistical methods that cover the following topics: (i) study design and sample size calculations, (ii) introduction to data analysis, and (iii) statistical computing (laboratory session). For more information, please complete the intake form CHI Intake Form.
- One-on-one consulting sessions. Up to five hours of no-cost consulting time is available for inquiries about study design and analysis. For more information, please complete the intake form CHI Intake Form.
- Multi-day workshops on advanced topics, including propensity scores models for observational data, hierarchical models for longitudinal/ multi-level studies, and latent class analysis. For more information on upcoming workshops, visit the following (http://chimb.ca/events).
We strongly encourage residents and fellows to undertake their own statistical analysis. However, for specialized analyses, residents and fellows may engage a biostatistical consultant on a fee-for-service basis. Some clinical departments may have specific funds set aside for training purposes to support the costs of a consultant. Please contact your department for further information about funding availability.
In addition, the Biostatistics Group offers workshops on the use of statistical software such as R, SAS, and SPSS. For more information, please visit http://chimb.ca/events
For inquiries, please complete CHI Intake Form.
The Bioinformatics and Computational Biology Group is a multidisciplinary team of computer science, statistics and biology faculty, staff, and students. We offer expertise in the analyses of big omics datasets for collaborative research projects and fee-for-service projects, including:
- Study design and analytical planning
- Sample size and power calculations
- Interpreting and summarizing results
- Assistance for developing grant proposals
We are specialized in (1) array-based gene expression, methylation and proteomic analysis; (2) DNA-Seq, RNA-Seq, Chip-Seq and methylation sequencing analysis; (3) statistical genetic analysis; (4) copy number variation analysis; (5) microbiome and metagenomic analysis; (6) pathway and/or gene set based analysis and enrichment map visualization.
For inquiries, please complete CHI Intake Form.
The Clinical Research Data Group serves as a resource for clinical researchers to develop new databases, and explore existing health databases in Manitoba. We aim to provide researchers with a central location for secure storage of clinical databases.
- Metadata Repository: a collection of metadata (data about data) that captures information about health status, factors that influence health status, health care, public health, and health–related interventions from the clinical trials, observational studies, and cohort studies in Manitoba. The Metadata Repository will help to promote the use of existing datasets for secondary analysis, thereby fostering research collaboration and innovation within Manitoba.
The Secure Research Environment (SRE) is a virtualized system maintained by MedIT of the Max Rady College of Medicine. It houses the local production instance of REDCap, a clinical research data management program supported by CHI, as well as a growing collection of analytic tools.
- Analysis of administrative health data, clinical registries, and electronic medical record data
For inquiry, please complete CHI Intake Form.
We offer fee-for-service consulting for researchers, clinicians, students and program staff. Some consulting is available free of charge, including study design an analysis planning for grant submissions. Graduate students, residents, and fellows have access to a limited amount of no-cost consulting services.
Dr. Lisa Lix joined the University of Manitoba in September 2012 as a Manitoba Research Chair and to lead the development of the Data Science platform within the George and Fay Yee Centre for Healthcare Innovation at the University of Manitoba. Prior to this, she was Centennial Chair in the School of Public Health at the University of Saskatchewan (2008 – 2012), and continues to direct a Population Health Data Laboratory at that University, funded by the Canadian Foundation for Innovation, which focuses on methodological techniques for the analysis of administrative health data.
Dr. Lix’s areas of research expertise include health services research methods, statistical methods for evaluation of the quality of administrative health databases, the analysis of repeated measures and longitudinal data, and robust statistical methods for patient-reported outcomes. She collaborates widely on projects about population health and the association between chronic disease and quality of life. Dr. Lix has extensive experience working with administrative health databases from multiple provinces and this has provided her with unique insights into new methodological research opportunities.
She is currently leading a three-year Canadian Institutes of Health Research (CIHR)-funded project that will conduct comparative investigations of the quality of physician billing claims databases from Newfoundland and Labrador, Nova Scotia, Manitoba, and Saskatchewan.
Director, Data Science
Dr. Robert Balshaw joined the Data Science Platform of the George and Fay Yee Centre for Healthcare Innovation as a Senior Biostatistician in the fall of 2017. Before this, Rob was a Senior Scientist for 5 years at the BC Centre for Disease Control, and for 14 years was head of biostatistics at Syreon Corporation (Vancouver), a contract research organization conducting clinical trials for the pharmaceutical industry. He obtained his bachelor’s and master’s degrees from the Department of Statistics at the University of Manitoba, and his PhD in Statistics from Simon Fraser University.
Dr. Balshaw’s expertise includes the planning, design, implementation and analysis of clinical trials, the discovery and validation of ‘omic biomarkers, secondary use of linked administrative databases, the use of observational data to approximate results of randomized studies, and the analysis of longitudinal and life-history data. He has collaborated with a wide variety of researchers, from graduate students through big pharma, and has led or been part of literally hundreds of statistical projects, big and small.
Loring Chuchmach received his M.Sc. in 2002 and has worked at the University of Manitoba since 1996. He joined the Data Science platform at Centre for Healthcare Innovation in 2015 as a data analyst, and prior to this he worked within several departments/faculties at the University of Manitoba including Kinesiology, Sociology, Nursing, and Psychology as both a research assistant and research associate. He has also done analytical contract work for the government of Manitoba. Along with working in the Data Science platform, Loring also holds an appointment in the department of Psychology as a research associate.
Loring has worked on a wide variety of projects, including longitudinal data on older adults (Aging in Manitoba, Successful Aging Projects), academic performance of university students (Motivation and Academic Achievement Study), and administrative health utilization data. Within the data science platform, he works with undergraduates, graduate students, residents, and clinicians to help them plan their projects and work with their collected data. He also provides guidance/instruction on how to manage and analyze data using SPSS.
Josie joined the Data Science Platform, the George & Fay Yee Centre for Healthcare Innovation in 2014. Prior to this, she was an office administrator for 10 years at the Department of Human Genetics, University of Manitoba. She has worked in different Business Units as an administrative assistant at the City of Calgary in 2003 to 2006 and was Digital Media Designer for 5 years at the City of Calgary. She has extensive experience and skills in an office and research environment to provide the research support to the members and trainees of the Data Science Platform.
Research Administrative Coordinator
Brenden Dufault received his MSc in Biostatistics & Epidemiology from the University of Western Ontario in 2009 and has been working as a statistical consultant ever since. He has collaborated with researchers in medicine, dentistry, psychology, nursing, public health, as well as government agencies and the pharmaceutical industry. Although a jack of trades, he specializes in mixed-effects models, latent class and trajectory analysis, and machine learning techniques such as random forests. He is slowly and tortuously transitioning to a Bayesian worldview.
Dr. Depeng Jiang is an Associate Professor in the Department of Community Health Sciences at the University of Manitoba and a lead of the Biostatistics group at the Data Science Platform within the George & Fay Yee Centre for Healthcare Innovation. Dr. Jiang had many years of experience in providing statistical consulting to a broad range of clients and training students and researchers on the conduct of statistical analyses. He is also an Adjunct Professor with OISE of University of Toronto and with Department of Psychology of York University. He also serves as a senior statistical advisor on several organizations (e.g., Child Development Institute, St. Michael’s Hospital).
Dr. Jiang’s program of research focuses on person-oriented statistical methods. His main research interests include longitudinal analysis and multilevel models, person-centered statistical approaches (latent class analysis and growth mixture models), structural equation models, clinical trial design and evaluation. Dr. Jiang is teaching several biostatistics courses in the Department's Graduate Program and currently supervises several graduate students and postdoctoral fellows.
Lead, Biostatistics Group
Dr. Pingzhao Hu received his Master’s degree from Dalhousie University and Ph.D in Computer Science from York University. Prior to joining the George and Fay Yee Centre for Healthcare Innovation, he was working as a research biostatistician and the manager of Statistical Analysis Facility for over ten years at the Centre for Applied Genomics of the Hospital for Sick Children, Toronto.
Currently, Dr. Hu is an Assistant Professor in the Department of Biochemistry and Medical Genetics and Adjunct Professor in the Department of Electrical and Computer Engineering at the University of Manitoba and Assistant Professor (Status) in Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto. His research focuses on statistical genetics and bioinformatics, especially on developing statistical and computational algorithms for integrative analysis of genomic data to understand the causal associations between human genome and phenome. Dr. Hu has published over 80 peer reviewed scientific articles with over 2,500 citations on high-profile journals, such as Cell, Nature Reviews Cancer, Nature Genetics, Plos Biology, Lancet Oncology, Cancer Research, American Journal of Human Genetics, Journal of the American Society of Nephrology, Nucleic Acids Research, etc. He has been supervising graduate students in bioinformatics, genetics, computer science and statistics.
Assistant Professor (Bioinformatics/Statistical Genetics)
Dr. Wattamon Srisakuldee obtained her Master’s degree and Ph.D from the Department Physiology and Pathophysiology, College of Medicine, at the University of Manitoba. She joined the Data Science Platform of the George & Fay Yee Centre for Healthcare Innovation in July 2016 as a Special Project Advisor. Her work involves the development of Metadata Repository in Manitoba. Prior to this, she was a Research Consultant at the Institute of Cardiovascular Sciences, St. Boniface Hospital Alberchtsen Research Centre, and was a Research Coordinator at the Manitoba Centre for Health Policy, University of Manitoba.
Special Projects Advisor
Dr. Rabbani is a biostatistician with the Data Science Platform at the George and Fay Yee Centre for Healthcare Innovation (CHI), as well as an Assistant Professor, Department of Community Health Sciences, University of Manitoba. She has over 10 years of experience in providing statistical consultation, collaboration and training to students and researchers in various specialties. She is an expert on both basic and advanced level of statistical methodologies. She has collaborated and co-authored on several prestigious publications. Her main research interest focuses on Meta-Analysis and Network Meta-Analysis specializing in synthesis projects. Currently she is offering lectures and workshops on meta-analysis in collaboration with the Knowledge Synthesis Platform at CHI. Prior to this position, she had served as a Biostatistician for the Children’s Hospital Research Institute of Manitoba (CHRIM). Dr. Rabbani had previously served as a senior scientist and Assistant Professor at numerous International institutes and Universities in Bangladesh. Dr. Rabbani completed her B.Sc. (Hons) and M.Sc. in Statistics from Jahangir Nagar University, Bangladesh and PhD in Agricultural Economics from Iwate University, Japan.
Dr. Lin Yan joined the George and Fay Yee Centre for Healthcare Innovation (CHI) as a Data Analyst in February 2013. Prior to joining CHI, Lin worked as a Research Analyst with the Saskatchewan Health Quality Council. Lin received a Master's degree in Public Health from the University of Saskatchewan, and a PhD in Pharmaceutics from the Sichuan University in China.
Data Coordinating Centre Manager
Abin Chandrakumar’s academic background is in Clinical Pharmacology—completed Pharm.D from Kerala University of Health Sciences in 2016 and graduated from the University of Manitoba in 2019 with a Master’s degree in Pharmacology & Therapeutics and was a recipient of this year's Governor General's Academic Gold Medal. Since 2018, Abin has been working in the Clinical Research Unit at the Children's Hospital Research Institute of Manitoba, initially as a research assistant and then as a research coordinator. As a clinical research professional, he has experience handling data for both industry-sponsored and investigator-sponsored studies using electronic data capture platforms like REDCap, Medidata Rave EDC and Endpoint IRT. Now, he is going to bring his background in clinical research and statistical analysis to develop new capabilities and functionalities in the Data Coordinating Centre (DCC).
Data Management Analyst
Naomi is a Research Data Manager in the Data Sciences Platform. Her work involves developing and offering data management strategies for the Data Science Platform that allows researchers to efficiently store, manage, and release data sets to other research team members while ensuring database security and confidentiality. Naomi received her MSc in Kinesiology at the University of Manitoba and her BSc (Hons) at the University of Saskatchewan.
Xuejing is a student on the Data Science Platform of CHI. She joined the team of CHI from May 2018 and worked on the Project 11, evaluation of mental health prevention program. Later in the September, she started her master program in Community Health Science from September 2017 with a concentration on biostatistics under the supervision of Dr. Depeng Jiang.
MSc Student, Junior Consultant
Yixiu is a data analyst in the CHI team and a master student working with Dr. Jiang in Biostatistics stream at University of Manitoba. She has the basic knowledge in Community Health Science field after finishing all the required courses this year. She also has solid mathematical and statistical knowledge, as well as good teaching skills, as she got her Master’s degree in Mathematics from Hainan Normal University and Bachelor’s degree with the same major from the same university.
Yixiu has basic programming skills of SAS and MATLAB as she has learnt SAS for one year and applied MATLAB as the simulation tool in her master’s thesis.
Allison joined the Data Science Platform in July 2018 and coordinates all aspects of the NSERC CREATE Visual and Automated Disease Analytics Program as well as the Manitoba Statistical and Health Sciences Collaborating Centre. She obtained her Bachelor of Health Sciences from the Department of Community Health Sciences at University of Manitoba.
Program Coordinator - Research and Training Programs
Dr. Sanusi completed his PhD in 2019 at City University of Hong Kong in the Department of Systems Engineering and Engineering Management. Prior to this, he completed undergraduate and Master’s degrees in statistics. Dr. Sanusi brings expertise in the analysis of time series data, including control chart methods. He will work with the Data Science platform on projects pertaining to statistical methods for longitudinal analysis of administrative health data and patient-reported outcomes data.
Dr. Amani Hamad completed her PhD at the University of Manitoba in the College of Pharmacy in 2019. Dr. Hamad brings expertise in pharmacoepidemiology and maternal child health, in addition to significant experience working with Manitoba’s administrative health data. Dr. Hamad will be working with Dr. Lisa Lix to plan the recently-funded research project entitled “Harnessing Population-Based Electronic Healthcare Records to Construct Family Health Histories for Accurate Disease Risk Prediction and Heritability Estimation.” As well, she will provide leadership in database development initiatives with the Canadian Network of Observational Drug Effect Studies (CNODES).
Dr. Razvan Romanescu joined the Data Science platform on January 20 as consulting biostatistician with the Biostatistics Group. Dr. Romanescu completed his PhD in 2016 at the University of Guelph. He then joined the Lunenfeld Research Institute at Mount Sinai Hospital in Toronto as a post-doctoral fellow. Dr. Romanescu’s expertise lies in statistical genetics, data-driven modeling, and infectious disease modeling.
Marcello Nesca has a diverse background with a focus on Research. Graduating with a B.Com (Hons) in 2005, he has worked in the telecommunications industry for close to 10 years with 8 of those years spent as a research analyst, business analyst, and a database analyst. After shifting gears, he has decided to enter the social sciences and acquire a B.A (Hons) in Psychology with a thesis in quantitative methods. Now, in the MSc program in Community Health Sciences, Marcello will specialize in Data Science and Statistics under the supervision of Dr Lisa Lix. His thesis focuses on finding tools to assess the quality of unstructured text data in electronic health databases. Concurrently with the MSc program, he is a student in the VADA program. His current research interests in quantitative methods are: Data quality, data visualization, data automation, Robust Statistics, and Structural equation modelling. Furthermore, he is interested in Knowledge Translation, in particular to quantitative methods, and Quantitative evaluation of programs/policy/process. Aside from academia, Marcello enjoys cooking, staying active, camping, and going out with friends and family.