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Ahmed Abou-Setta MD, PhD

Dr. Ahmed Abou-Setta is currently the Manager, Knowledge Synthesis, The George and Fay Yee Centre for Healthcare Innovation, University of Manitoba/ Winnipeg Regional Health Authority and an Assistant Professor, Community Health Sciences, College of Medicine, Faculty of Health Sciences. In this role, he leads and supports knowledge synthesis projects including clinical guideline preparation, systematic reviews, overviews of reviews and related activities. In addition, Dr. Abou-Setta is leading innovative research into methods for improving and streamlining the systematic review process including the use of computer-assisted screening and probability-based classification of citations, increasing visual identification of key terms using system-generated font and color contrast, computer-assisted literature search strategy production, and semi-automated report preparation. Furthermore, Dr. Abou-Setta is involved in continuous education to clinical faculty at the University of Manitoba and students through epidemiological and biostatistical consultation, teaching, and collaborative innovative research on knowledge synthesis projects.

Dr. Abou-Setta’s areas of research expertise includes clinical epidemiological research methods, methods for evaluation of the quality of data from clinical trials, the meta-analysis of trial data, and methods for utilizing indirect evidence. He has engaged in research synthesis, data analysis, meta-analysis, interpretation, presentation and review and methodology consultations with different groups from all over the world, including collaborating with world-renowned clinicians, epidemiologists and researchers, including members of The Egyptian and Middle East IVF registries, and the International Committee for Monitoring IVF. Most recently, he has completed a postdoctoral fellowship at the University of Alberta’s Evidence-based Practice Centre, where he led multiple teams of review authors to investigate important clinical questions in the context of comparative effectiveness reviews and methodological reviews.

Dr. Abou-Setta combines unique insights as both a clinician and post-doctorate level researcher with research experience in various clinical settings. These clinical topics are broad and have included reproductive endocrinology, pain management in elderly patients with hip fractures, management strategies in hypercholesterolemic patients, antipsychotic management of adults with schizophrenia and bipolar disorder, management of male impotence, and prevention of premature ovarian failure in women undergoing chemotherapy.

Dr. Abou-Setta is highly committed to creating and sustaining educational opportunities and training in the knowledge and skills essential to undertake knowledge synthesis projects. As none were available at the University of Manitoba, Dr. Abou-Setta has been co-teaching the first accredited systematic review course where graduate students and clinicians at the University of Manitoba are being trained to produce high-quality systematic reviews of the literature. In addition, Dr. Abou-Setta is exploring opportunities to collaborate with well-established organization like the Cochrane Collaboration and other Canadian Universities to provide local training to the University of Manitoba’s members, especially in advanced methods like network meta-analysis, individual patient meta-analysis and rapid reviews.

The excellence of Dr. Abou-Setta’s research agenda has been recognized through frequent presentation of results at international venues including the Cochrane Colloquium, multiple publications in top-ranked peer-reviewed journals including the JAMA, Annals of Internal Medicine, Cochrane Library, and publications having been cited over 600 times (H-index = 14).

Contact Information

Name: Ahmed Abou-Setta MD, PhD
Title: Director, Knowledge Synthesis platform
Degree: MD, PhD
Phone: 204.594.5357
Fax: 204.594.5394

Publications >

The Cochrane database of systematic reviews, 2018,

Application of seminal plasma to female genital tract prior to embryo transfer in assisted reproductive technology cycles (IVF, ICSI and frozen embryo transfer).


Show in PubMed - PMID:29489026

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More publications

Clinical Practice Guideline on Screening for Colorectal Cancer in individuals with a Family History of Nonhereditary Colorectal Cancer or Adenoma: The Canadian Association of Gastroenterology Banff Consensus.
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Nonnutritive sweeteners and cardiometabolic health: a systematic review and meta-analysis of randomized controlled trials and prospective cohort studies.
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Behavior change interventions and policies influencing primary healthcare professionals' practice-an overview of reviews.
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Methods for Developing Evidence Reviews in Short Periods of Time: A Scoping Review.
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Association of Pre-hospital ECG Administration With Clinical Outcomes in ST-Segment Myocardial Infarction: A Systematic Review and Meta-analysis.
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Chemoradiotherapy versus radiotherapy alone in elderly patients with stage III non-small cell lung cancer: A systematic review and meta-analysis.
PMID: 27565937

Systematic review of interventions for depression and anxiety in persons with inflammatory bowel disease.
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Recombinant versus urinary human chorionic gonadotrophin for final oocyte maturation triggering in IVF and ICSI cycles.
PMID: 27106604

Ultrasound versus 'clinical touch' for catheter guidance during embryo transfer in women.
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Early Exposure to Nonnutritive Sweeteners and Long-term Metabolic Health: A Systematic Review.
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New modalities to deliver surfactant in premature infants: a systematic review and meta-analysis.
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Systematic review and meta-analysis of interventions for depression and anxiety in persons with multiple sclerosis.
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Severe Rh alloimmunization and hemolytic disease of the fetus managed with plasmapheresis, intravenous immunoglobulin and intrauterine transfusion: A case report.
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Clinical trial registries are of minimal use for identifying selective outcome and analysis reporting.
PMID: 26052852

Rapid review programs to support health care and policy decision making: a descriptive analysis of processes and methods.
PMID: 25874967

The efficacy and safety of plasma exchange in patients with sepsis and septic shock: a systematic review and meta-analysis.
PMID: 25527094

The efficacy and safety of heparin in patients with sepsis: a systematic review and metaanalysis.
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A systematic review and meta-analysis of exercise interventions in adults with type 1 diabetes.
PMID: 25451913

Post-embryo transfer interventions for assisted reproduction technology cycles.
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Pain management with acupuncture in osteoarthritis: a systematic review and meta-analysis.
PMID: 25151529

The impact of omega-3 polyunsaturated fatty acid supplementation on the incidence of cardiovascular events and complications in peripheral arterial disease: a systematic review and meta-analysis.
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Probiotic supplementation during pregnancy or infancy for the prevention of asthma and wheeze: systematic review and meta-analysis.
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Role of the levonorgestrel intrauterine system in effective contraception.
PMID: 23990713

Gonadotrophins for idiopathic male factor subfertility.
PMID: 23970458

Economic evaluation of highly purified human menopausal gonadotropin versus recombinant human follicle-stimulating hormone in fresh and frozen in vitro fertilization/intracytoplasmic sperm-injection cycles in Sweden.
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Leuprolide acetate 1-, 3- and 6-monthly depot formulations in androgen deprivation therapy for prostate cancer in nine European countries: evidence review and economic evaluation.
PMID: 23836996

Meta-analyses of hydroxyethyl starch for volume resuscitation--reply.
PMID: 23736723

Levonorgestrel-releasing intrauterine device (LNG-IUD) for symptomatic endometriosis following surgery.
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Association of hydroxyethyl starch administration with mortality and acute kidney injury in critically ill patients requiring volume resuscitation: a systematic review and meta-analysis.
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Efficacy of supplemental peripheral nerve blockade for hip fracture surgery: multiple treatment comparison.
PMID: 23334780

Gonadatrophin suppression to prevent chemotherapy-induced ovarian damage: a randomized controlled trial.
PMID: 23262931