Bioinfomatics-Biostatistics Journal Club and Research Seminar : Understanding genetic basis of imaging phenotypes through genome-wide mediation analysis


Bioinfomatics-Biostatistics Journal Club and Research Seminar : Understanding genetic basis of imaging phenotypes through genome-wide mediation analysis

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January 28, 2020 - 11:00 - 12:00
Team: Events, Training & News
Posted on October 08, 2019
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Bioinfomatics-Biostatistics Journal Club and Research Seminar : Understanding genetic basis of imaging phenotypes through genome-wide mediation analysis

Team: Events, Training & News

January 28, 2020 - 11:00 - 12:00

Description


Understanding genetic basis of imaging phenotypes through genome-wide mediation analysis

January 28, 2020
11:00 am - 12:00 pm
Klaus Wrogemann Seminar Room 341 Basic Medical Sciences Building

DISCUSSION LEAD

Qian Liu, PhD Student (Dr. Pingzhao Hu Lab)
Individual Interdisciplinary Studies Program, University of Manitoba

OBJECTIVE

We will discuss the utilization of mediation analyses to discover  mechanisms where genetic variants may have influence on complex traits implicitly through intermediate and deep imaging phenotypes..

READINGS

Bi et al. Genome-wide mediation analysis of psychiatric and cognitive traits through imaging phenotypes. Human Brain Mapping. 2017; 38:4088–4097. 

A Schizophrenia-Related Genetic-Brain-Cognition Pathway Revealed in a Large Chinese Population. Luo et a. . EBioMedicine. 2018, 37:471-482; https://doi.org/10.1016/j.ebiom.2018.10.009


Bioinformatics-Biostatistics Journal Club and Research Seminar Series is hosted by the Data Science Platform at the George & Fay Yee Centre for Healthcare Innovation. It aims to stimulate discussion of computational and statistical method developments and applications for complex health data in translational and personalized medicine. All students, faculty, and staff are welcome to join this monthly event. All previous talks can be found at http://www.hu-bioinformaticslab.org/journal-club.html

For more information, contact Dr. Pingzhao Hu at pingzhao.hu@umanitoba.ca or Dr. Robert Balshaw at Robert.Balshaw@umanitoba.ca.

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