Data Science


About CHI Data Science

The Data Science Platform facilitates the development, management, analysis, and linkage of clinical, administrative, genomic and other data resources for patient-oriented research. The Platform works closely with the Manitoba Centre for Health Policy (MCHP), Regional Health Authorities, Manitoba Health, Seniors and Active Living, Public Health Agency of Canada, Canada Institute for Health Information, other provincial/ territorial SPOR SUPPORT Units, and other stakeholders.

We are comprised of three groups:
(1) Biostatistic Group
(2) Bioinformatics and Computational Biology Group                         
(3) Clinical Research Data Group 

 

RESEARCH

Scientists lead and participate in a variety of projects to improve patient outcomes. Methodological innovations have focused on:

  • Modelling of genomics and microbiome data
  • Database quality assessment
  • Population health surveillance methods
  • Disease risk prediction models
  • Measuring and modeling latent variables, such as health-related quality of life

 

TRAINING

Our team offers a range of short courses, workshops, and seminars including:

  • Biostatistics group consulting sessions
  • Workshops on advanced statistical methods, such as propensity score models and missing data models
  • Resident training sessions on introductory biostatistics
  • Bioinformatics workshops
  • Introductory and intermediate clinical data management workshops
  • Internships for undergraduate and graduate students

 

Biostatistics Group

The Biostatistics Group serves as a resource of statistical expertise for researchers and students across the University of Manitoba, as well as at other universities. Expertise is provided in design, measurement, and analysis of health and health-related data.

The Biostatistics Group operates on a cost recovery model, however, there are accommodations for students and faculty members who do not have funds to support their research.

Examples of academic collaborations include:

• Consults on research design, data collection, data analysis, and results interpretation.
• Develops and adapts new research methods for research projects.
• Participates in grant planning, and proposal development.
• Provides advice on statistical computing for a variety of software, including SAS, SPSS, R and M-plus.
• Sample size and power calculations.

 

Support for New Clinician Scientists

The Biostatistics Group offers multiple training opportunities for the next generation of clinician scientists. The Royal College of Physicians and Surgeons has added a new scholarly competency to their training standards for resident and fellows (CanMEDS 2015), which will oblige trainees to formally study research methods and conduct a scholarly or research project during their training. To support resident and fellow research, the Biostatistics Group offers the following complementary programs and services:

  • Open House sessions, where residents and fellows can meet one or more biostatistical consultants to discuss their study design and analysis questions. These sessions are co-sponsored by the College of Medicine’s Office of Postgraduate Medical Education (PGME). Registration is required, but there are no costs to participate. Please contact the PGME office for more information (pgme@umanitoba.ca).
  • A series of 3 academic half day workshops on statistical methods that cover the following topics: (i) study design and sample size calculations, (ii) introduction to data analysis, and (iii) statistical computing (laboratory session). For more information, please complete the intake form CHI Intake Form.
  • One-on-one consulting sessions. Up to five hours of no-cost consulting time is available for inquiries about study design and analysis. For more information, please complete the intake form CHI Intake Form.
  • Multi-day workshops on advanced topics, including propensity scores models for observational data, hierarchical models for longitudinal/ multi-level studies, and latent class analysis. For more information on upcoming workshops, visit the following (http://chimb.ca/events).

We strongly encourage residents and fellows to undertake their own statistical analysis. However, for specialized analyses, residents and fellows may engage a biostatistical consultant on a fee-for-service basis. Some clinical departments may have specific funds set aside for training purposes to support the costs of a consultant. Please contact your department for further information about funding availability.

In addition, the Biostatistics Group offers workshops on the use of statistical software such as R, SAS, and SPSS. For more information, please visit http://chimb.ca/events

Contact:
 
For inquiries, please complete CHI Intake Form.

Bioinformatics and Computational Biology Group

The Bioinformatics and Computational Biology Group is a multidisciplinary team of computer science, statistics and biology faculty, staff, and students.  We offer expertise in the analyses of big omics datasets for collaborative research projects and fee-for-service projects, including:

  • Study design and analytical planning
  • Sample size and power calculations
  • Interpreting and summarizing results
  • Assistance for developing grant proposals

We are specialized in (1) array-based gene expression, methylation and proteomic analysis; (2) DNA-Seq, RNA-Seq, Chip-Seq and methylation sequencing analysis; (3) statistical genetic analysis;  (4) copy number variation analysis; (5) microbiome and metagenomic analysis; (6) pathway and/or gene set based analysis and enrichment map visualization.

Contact:

  For inquiries, please complete CHI Intake Form.

 

 

Clinical Research Data Group

The Clinical Research Data Group serves as a resource for clinical researchers to develop new databases, and explore existing health databases in Manitoba. We aim to provide researchers with a central location for secure storage of clinical databases.

  • Metadata Repository: a collection of metadata (data about data) that captures information about health status, factors that influence health status, health care, public health, and health–related interventions from the clinical trials, observational studies, and cohort studies in Manitoba. The Metadata Repository will help to promote the use of existing datasets for secondary analysis, thereby fostering research collaboration and innovation within Manitoba.
  • The Secure Research Environment (SRE) is a virtualized system maintained by MedIT of the Max Rady College of Medicine. It houses the local production instance of REDCap, a clinical research data management program supported by CHI, as well as a growing collection of analytic tools.

  • Analysis of administrative health data, clinical registries, and electronic medical record data

Contact:
 
For inquiry, please complete CHI Intake Form.

 

 

 

Our Services

We offer fee-for-service consulting for researchers, clinicians, students and program staff. Some consulting is available free of charge, including study design an analysis planning for grant submissions. Graduate students, residents, and fellows have access to a limited amount of no-cost consulting services.

Our Team

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Lisa Lix, PhD P.Stat

Director, Data Science

Dr. Lisa Lix joined the University of Manitoba in September 2012 as a Manitoba Research Chair and to lead the development of the Data Science platform within the George and Fay Yee Centre for Healthcare Innovation at the University of Manitoba. Prior to this, she was Centennial Chair in the School of Public Health at the University of Saskatchewan (2008 – 2012), and continues to direct a Population Health Data Laboratory at that University, funded by the Canadian Foundation for Innovation, which focuses on methodological techniques for the analysis of administrative health data.

Dr. Lix’s areas of research expertise include health services research methods, statistical methods for evaluation of the quality of administrative health databases, the analysis of repeated measures and longitudinal data, and robust statistical methods for patient-reported outcomes. She collaborates widely on projects about population health and the association between chronic disease and quality of life. Dr. Lix has extensive experience working with administrative health databases from multiple provinces and this has provided her with unique insights into new methodological research opportunities.

She is currently leading a three-year Canadian Institutes of Health Research (CIHR)-funded project that will conduct comparative investigations of the quality of physician billing claims databases from Newfoundland and Labrador, Nova Scotia, Manitoba, and Saskatchewan.

 
Websites: http://home.cc.umanitoba.ca/~lixlm/

tel: 204.789.3573
fax: 204.789.3905
email: lisa.lix@umanitoba.ca


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Robert Balshaw, PhD

Senior Biostatistician

In the fall of 2017, Dr. Robert Balshaw returned to the University of Manitoba to join the Data Science Platform of the George and Fay Yee Centre for Healthcare Innovation as a Senior Biostatistician.  Prior to this, he was a Senior Scientist at the BC Centre for Disease Control for almost five years, and for 14 years was the head of biostatistics at Syreon Corporation (Vancouver), a contract research organization working with the pharmaceutical industry.  He is a native Winnipegger and obtained his bachelor’s and master’s degrees from the Department of Statistics at the University of Manitoba, as well as a PhD in education. He also ran the Statistical Advisory Service in the early 1990’s.

Dr. Balshaw’s research expertise includes clinical trials, the discovery and validation of ‘omic biomarkers, database studies, the use of observational data to approximate results of randomized studies, and the analysis of longitudinal and life-history data.  He has collaborated with a wide variety of researchers, from graduate students through big pharma, and has led or been part of literally hundreds of statistical projects, big and small.

tel: 204.594.5370
email: robert.balshaw@umanitoba.ca


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Dennis Bayomi, MSc

Research Data Administrator (REDCap Training and Support Lead)

Dennis Bayomi is the Research Data Administrator, serving as CHI's REDCap training and support lead. He organizes and conducts training sessions for research teams interested in using REDCap and provides support for projects using that system.

Since 2001, Dennis has also been working part-time as a database/research analyst for the Manitoba Follow-up Study (UM Community Health Sciences), one of the longest-running longitudinal studies in the world. Prior to that, he worked for over a decade as the Faculty of Medicine's IT Coordinator.

Dennis has a B.Sc. (Honors) degree in Computer Science and M.Sc. in Community Health Sciences, both from the University of Manitoba.

He’s a founder and active participant in several Bannatyne Campus community outreach programs: Basketballs for Inner City Kids, SWISH (Summer Weekend Inner-city Supervised Hoops) and the Inner City Kids’ Computer Club.

tel: 204.594.5371
fax: 204.594.5394
email: Dennis.Bayomi@umanitoba.ca


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Brenden Dufault, , MSc

Biostatistician

Brenden Dufault received his MSc in Biostatistics & Epidemiology from the University of Western Ontario in 2009 and has been working as a statistical consultant ever since. He has collaborated with researchers in medicine, dentistry, psychology, nursing, public health, as well as government agencies and the pharmaceutical industry. Although a jack of trades, he specializes in mixed-effects models, latent class and trajectory analysis, and machine learning techniques such as random forests. He is slowly and tortuously transitioning to a Bayesian worldview.

tel: 204.594.5369
fax: 204.594.5394
email: Brenden.Dufault@umanitoba.ca


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Loring Chuchmach, MSc

Analyst

Loring Chuchmach received his M.Sc. in 2002 and has worked at the University of Manitoba since 1996.  He joined the Data Science platform at Centre for Healthcare Innovation in 2015 as a data analyst, and prior to this he worked within several departments/faculties at the University of Manitoba including Kinesiology, Sociology, Nursing, and Psychology as both a research assistant and research associate.   He has also done analytical contract work for the government of Manitoba.  Along with working in the Data Science platform, Loring also holds an appointment in the department of Psychology as a research associate.

Loring has worked on a wide variety of projects, including longitudinal data on older adults (Aging in Manitoba, Successful Aging Projects), academic performance of university students (Motivation and Academic Achievement Study), and administrative health utilization data. Within the data science platform, he works with undergraduates, graduate students, residents, and clinicians to help them plan their projects and work with their collected data.  He also provides guidance/instruction on how to manage and analyze data using SPSS.

tel: 204.789.3714
fax: 204.594.5394
email: loring.chuchmach@umanitoba.ca


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Josephine Diato

Research Administrative Coordinator

Josie joined the Data Science Platform, the George & Fay Yee Centre for Healthcare Innovation in 2014. Prior to this, she was an office administrator for 10 years at the Department of Human Genetics, University of Manitoba. She has worked in different Business Units as an administrative assistant  at the City of Calgary in 2003 to 2006 and was Digital Media Designer for 5 years at the City of Calgary. She has extensive experience and skills in an office and research environment to provide the research support to the members and trainees of the Data Science Platform.

tel: 204.480.1367
fax: 204.594.5394
email: Josephine.Diato@umanitoba.ca


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Kristine Kroeker, MSc

Data Analyst

Kristine is a Data Analyst in the Data Science Platform mainly working with Manitoba’s administrative data and clinical databases. She leads workshops in R Studio. She completed her B.Sc (Hons) in Statistics and M.Sc in Community Health Sciences both from the University of Manitoba.

tel: 204.594.5374
fax: 204.594.5394
email: kristine.kroeker@umanitoba.ca


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Pingzhao Hu, PhD

Assistant Professor (Bioinformatics/Statistical Genetics)

Dr. Pingzhao Hu received his Master’s degree from Dalhousie University and Ph.D in Computer Science from York University. Prior to joining the George and Fay Yee Centre for Healthcare Innovation, he was working as a research biostatistician and the manager of Statistical Analysis Facility for over ten years at the Centre for Applied Genomics of the Hospital for Sick Children, Toronto.  

 

Currently, Dr. Hu is an Assistant Professor in the Department of Biochemistry and Medical Genetics and Adjunct Professor in the Department of Electrical and Computer Engineering at the University of Manitoba and Assistant Professor (Status) in Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto. His research focuses on statistical genetics and bioinformatics, especially on developing statistical and computational algorithms for integrative analysis of genomic data to understand the causal associations between human genome and phenome. Dr. Hu has published over 80 peer reviewed scientific articles with over 2,500 citations on high-profile journals, such as Cell, Nature Reviews Cancer, Nature Genetics, Plos Biology, Lancet Oncology, Cancer Research, American Journal of Human Genetics, Journal of the American Society of Nephrology, Nucleic Acids Research, etc. He has been supervising graduate students in bioinformatics, genetics, computer science and statistics.

Website: http://www.hu-bioinformaticslab.org.

tel: 204.789.3229
fax: 204.594.5394
email: Pingzhao.Hu@umanitoba.ca



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Depeng Jiang, PhD

Lead, Biostatistics Group

Dr. Depeng Jiang is an Associate Professor in the Department of Community Health Sciences at the  University of Manitoba and a lead of the Biostatistics group at the Data Science Platform within the George & Fay Yee Centre of Health Innovation.  Dr. Jiang had many years of experience in providing statistical consulting to a broad range of clients and training students and researchers on the conduct of statistical analyses. He is also an Adjunct Professor with OISE of University of Toronto and with Department of Psychology of York University. He also serves as a senior statistical advisor on several organizations (e.g., Child Development Institute, St. Michael’s Hospital).

Dr. Jiang’s program of research focuses on person-oriented statistical methods. His main research interests include longitudinal analysis and multilevel models, person-centered statistical approaches (latent class analysis and growth mixture models), structural equation models, clinical trial design and evaluation. Dr. Jiang is teaching several biostatistics courses in the Department's Graduate Program and currently supervises several graduate students and postdoctoral fellows.

tel: 204.272.3137
fax: 204.789.3905
email: Depeng.Jiang@umantioba.ca


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Rasheda Rabbani, PhD

Biostatistician

 

Dr. Rabbani is a biostatistician with the Data Science Platform at the George and Fay Yee Centre for Healthcare Innovation (CHI), as well as an Assistant Professor, Department of Community Health Sciences, University of Manitoba. She has over 10 years of experience in providing statistical consultation, collaboration and training to students and researchers in various specialties. She is an expert on both basic and advanced level of statistical methodologies. She has collaborated and co-authored on several prestigious publications. Her main research interest focuses on Meta-Analysis and Network Meta-Analysis specializing in synthesis projects. Currently she is offering lectures and workshops on meta-analysis in collaboration with the Knowledge Synthesis Platform at CHI. Prior to this position, she had served as a Biostatistician for the Children’s Hospital Research Institute of Manitoba (CHRIM). Dr. Rabbani had previously served as a senior scientist and Assistant Professor at numerous International institutes and Universities in Bangladesh. Dr. Rabbani completed her B.Sc. (Hons) and M.Sc. in Statistics from Jahangir Nagar University, Bangladesh and PhD in Agricultural Economics from Iwate University, Japan.

 

 

tel: 204.594.5375
fax: 204.594.5394
email: Rasheda.Rabbani@umanitoba.ca


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Wattamon Srisakuldee, PhD

Special Project Advisor

Dr. Wattamon Srisakuldee obtained her Master’s degree and Ph.D from the Department Physiology and Pathophysiology, College of Medicine, at the University of Manitoba. She joined the Data Science Platform of the George & Fay Yee Centre for Healthcare Innovation in July 2016 as a Special Project Advisor. Her work involves the development of Metadata Repository in Manitoba. Prior to this, she was a Research Consultant at the Institute of Cardiovascular Sciences, St. Boniface Hospital Alberchtsen Research Centre, and was a Research Coordinator at the Manitoba Centre for Health Policy, University of Manitoba.

tel: 204.594.5368
fax: 204.594.5394
email: Wattamon.Srisakuldee@umanitoba.ca


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Lin Yan, PhD

Data Analyst

Dr. Lin Yan joined the George and Fay Yee Centre for Healthcare Innovation (CHI) as a Data Analyst in February 2013. Prior to joining CHI, Lin worked as a Research Analyst with the Saskatchewan Health Quality Council. Lin received a Master's degree in Public Health from the University of Saskatchewan, and a PhD in Pharmaceutics from the Sichuan University in China.

tel: 204.594.5373
fax: 204.594.5394
email: lin.yan@umanitoba.ca


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Naomi Hamm, MSc, BSc

Research Data Manager

Naomi is a Research Data Manager in the Data Sciences Platform. Her work involves developing and offering data management strategies for the Data Science Platform that allows researchers to efficiently store, manage, and release data sets to other research team members while ensuring database security and confidentiality.  Naomi received her MSc in Kinesiology at the University of Manitoba and her BSc (Hons) at the University of Saskatchewan.

tel: 204.789.3526
email: lettn@myumanitoba.ca


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Svetlana Frenkel, PhD

Post-Doctoral Fellow

Dr. Svetlana Frenkel received a Master’s degree in Medical Cybernetics from the Siberian State Medical University, Russia and Ph.D in Computational Biology from the University of Haifa, Israel. Currently, Dr. Frenkel is a postdoctoral researcher of bioinformatics in the Hu’s lab in the Department of Biochemistry and Medical Genetics and Data Science Platform of George and Fay Yee Centre for Healthcare Innovation at the University of Manitoba.

tel: 204.789.3805
email: svetlana.frenkel@umanitoba.ca


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Iraj Yadegari, PhD

Post-Doctoral Fellow

Iraj Yadegari is a Post-Doctoral Fellow in the Data Science Platform at the George & Fay Yee Centre for Healthcare Innovation at the University of Manitoba. He has a BSc and MSc in statistics from Iran, and a Ph.D. in statistics from the University of Sherbrooke, Quebec, Canada. His Ph.D. research was mainly focused on prediction and selective inference. A key focus of Iraj’s post-doctoral research will be to work on statistical modeling and inference on patient-reported outcome measures.

tel: 204.480.1371
email: iraj.yadegari@umanitoba.ca


Training Opportunities

Our team offers Co-op and practicum students from undergraduate and graduate programs in statistics, biostatistics, and epidemiology an opportunity to gain practical experience in working with interdisciplinary teams of investigators. Examples of previous students’ projects include:

  • Multimorbidity surveillance methods
  • Risk prediction model development
  • Analysis techniques for patient-reported outcome measures
  • Missing data models